Call Us  :  +918447679450
Mail Us :
Join Us :

Homeo Foundation


Adrenocortical Carcinoma :

Adrenocortical carcinoma is a disease in which malignant (cancer) cells form in the outer layer of the adrenal gland.

There are two adrenal glands. Each adrenal gland has two parts. The outer layer of the adrenal gland is the adrenal cortex. The center of the adrenal gland is the adrenal medulla.

  • The adrenal cortex makes important hormones that:
  • Balance the water and salt in the body.
  • Help keep blood pressure normal.
  • Help manage the body’s use of protein, fat, and carbohydrates.
  • Cause the body to have masculine or feminine characteristics.

The adrenal medulla makes hormones that help the body react to stress.

A tumour of the adrenal cortex may be functioning (makes more hormones than normal) or nonfunctioning (does not make hormones). The hormones made by functioning tumours may cause certain signs or symptoms of disease.

Certain genetic conditions ( hereditary diseases) increases the chances of developing adrenocortical carcinoma and are as follows

  • Li-Fraumeni syndrome.
  • Beckwith-Wiedemann syndrome.
  • Carney complex.


  • A lump in the abdomen.
  • Pain the abdomen or back.

Non functioning adrenocortical tumor may not cause symptoms in the early stages. Functioning adrenocortical tumor makes too much of a certain hormone (cortisol, aldosterone, testosterone, or estrogen) and of those hormones as follows:

Too much cortisol may cause:

  • Weight gain in the face, neck, and trunk of the body and thin arms and legs.
  • Growth of fine hair on the face, upper back, or arms.
  • A round, red, full face.
  • A lump of fat on the back of the neck.
  • A deepening of the voice and swelling of the sex organs or breasts in both males and females.
  • Muscle weakness.
  • High blood sugar.
  • High blood pressure.

Too much aldosterone may cause:

  • High blood pressure.
  • Muscle weakness or cramps.
  • Frequent urination.
  • Feeling thirsty.

Too much testosterone (in women) may cause:

  • Growth of fine hair on the face, upper back, or arms.
  • Acne.
  • Balding.
  • A deepening of the voice.
  • No menstrual periods.

Too much estrogen (in women) may cause:

  • Irregular menstrual periods in women who have not gone through menopause.
  • Menstrual bleeding in women who have gone through menopause.

Too much estrogen (in men) may cause:

  • Growth of breast tissue.
  • Lower sex drive.
  • Impotence.

These and other symptoms may be caused by adrenocortical carcinoma. Other conditions may cause the same symptoms. A doctor should be consulted if any of these problems.


Contact Us or visit us for treatment.